Tech coach John Heisman challenged Pitt coach Pop Warner to a postseason contest to determine a national champion, but as such a match did not occur until the next season, Tech was named national champion. The Golden Tornado was invited to play a 4–3 Oregon team in the Rose Bowl, but by then many players had joined the war effort.
In the second week of play, Georgia Tech beat Penn 41–0. Bernie McCarty called it "Strupper's finest hour, coming through against powerful Penn in the contest that shocked the East." By comparison, Pitt defeated Penn 14–6.
Georgia Tech gave Vanderbilt its worst ever beating, 83–0.Auburn crushed Florida 68–0. Centre beat Kentucky 3–0. Texas A&M beat Tulane 35–0. Wisconsin beat Minnesota 10–7. Illinois tied Chicago 0–0. Rutgers tied West Virginia 3–3.
A freshman Buck Flowers at Davidson upset Auburn 21–7. All of Georgia Tech's backs rushed for 100 yards in a 48–0 defeat of Tulane. Texas A&M beat Baylor 7–0. Ohio State beat Wisconsin 16–3. Navy beat Georgetown 28–7.
Georgia Tech beat Carlisle 98–0. Penn beat Michigan 16–0. Ohio State beat Illinois 13–0.
Auburn fought undefeated Ohio State to a scoreless tie. Coach Heisman of Georgia Tech(who previously coached at Auburn) and his players were at the game, rooting for the Tigers. Minnesota beat Illinois 27–6.
Georgia Tech beat Auburn 68 to 7. Davidson beat Clemson 21–9. Mississippi A&M beat Haskell 7–6.