AQP7

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AQP7
Identifiers
AliasesAQP7, AQP7L, AQP9, AQPap, GLYCQTL, aquaporin 7
External IDsOMIM: 602974 MGI: 1314647 HomoloGene: 48000 GeneCards: AQP7
Gene location (Human)
Chromosome 9 (human)
Chr.Chromosome 9 (human)[1]
Chromosome 9 (human)
Genomic location for AQP7
Genomic location for AQP7
Band9p13.3Start33,383,179 bp[1]
End33,402,682 bp[1]
RNA expression pattern
PBB GE AQP7 206955 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007473

RefSeq (protein)

NP_031499

Location (UCSC)Chr 9: 33.38 – 33.4 MbChr 4: 41.03 – 41.05 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Aquaporin-7 is a protein that in humans is encoded by the AQP7 gene.[5][6]

Aquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in thermoregulation in the form of perspiration and sperm function.[6]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000165269 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028427 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ishibashi K, Kuwahara M, Gu Y, Kageyama Y, Tohsaka A, Suzuki F, Marumo F, Sasaki S (Sep 1997). "Cloning and functional expression of a new water channel abundantly expressed in the testis permeable to water, glycerol, and urea". J Biol Chem. 272 (33): 20782–6. doi:10.1074/jbc.272.33.20782. PMID 9252401.
  6. ^ a b "Entrez Gene: AQP7 aquaporin 7".

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.