CLEC10A Identifiers Aliases , CD301, CLECSF13, CLECSF14, HML, HML2, MGL, C-type lectin domain family 10 member A, C-type lectin domain containing 10A CLEC10A External IDs OMIM: 605999 MGI: 96975 HomoloGene: 7836 GeneCards: CLEC10A
Gene location (Mouse) Chr. Chromosome 11 (mouse)  Band 11 B3|11 42.99 cM Start 70,156,197 bp  End 70,170,834 bp  Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 17: 7.07 – 7.08 Mb Chr 11: 70.16 – 70.17 Mb PubMed search   Wikidata
C-type lectin domain family 10 member A also known as CLEC10A is a protein that in humans is encoded by the CLEC10A gene.
Function [ edit ]
This gene encodes a member of the
C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene.
References [ edit ]
External links [ edit ]
Further reading [ edit ]
Bonaldo MF, Lennon G, Soares MB (1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: . 10.1101/gr.6.9.791 PMID 8889548.
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi: 10.1073/pnas.242603899. PMC . 139241 PMID 12477932.
van Vliet SJ, Steeghs L, Bruijns SC, et al. (2009). Seifert HS (ed.). "Variation of Neisseria gonorrhoeae Lipooligosaccharide Directs Dendritic Cell–Induced T Helper Responses". PLOS Pathog. 5 (10): e1000625. doi: 10.1371/journal.ppat.1000625. PMC . 2757725 PMID 19834553.
Iijima M, Tomita M, Morozumi S, et al. (2009). "Single nucleotide polymorphism of TAG-1 influences IVIg responsiveness of Japanese patients with CIDP". Neurology. 73 (17): 1348–52. doi: 10.1212/WNL.0b013e3181bd1139. PMID 19776380. S2CID 207116106. Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi: 10.1101/gr.2596504. PMC . 528928 PMID 15489334. This article incorporates text from the
United States National Library of Medicine, which is in the public domain.