DTaP-IPV/Hib vaccine

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DTaP-IPV/Hib vaccine
Combination of
DTaP vaccineVaccine
Inactivated poliovirus vaccineVaccine
Hib vaccineVaccine
Clinical data
Trade namesPentacel, Pediacel, Infanrix IPV + Hib, others
AHFS/Drugs.comFDA Professional Drug Information
  • US: C (Risk not ruled out) [1]
Routes of
Intramuscular injection
ATC code
Legal status
Legal status

DTaP-IPV/Hib vaccine is a combination vaccine whose generic name is diphtheria and tetanus toxoids and acellular pertussis adsorbed, inactivated poliovirus and haemophilus B conjugate (tetanus toxoid conjugate) vaccine.[2] It is also known as DTaP-IPV/Hib or DTaP-IPV-Hib. It protects against the infectious diseases diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type B.

A branded formulation marketed in the United States is Pentacel, manufactured by Sanofi Pasteur.[3] Pentacel is known in the UK and Canada as Pediacel.[4][5] An equivalent vaccine marketed in the UK and Canada by GlaxoSmithKline is Infanrix IPV + Hib.[5] This is a two-part vaccine. The DTaP-IPV component is supplied as a sterile liquid, which is used to reconstitute lyophilized (freeze-dried) Hib vaccine.

Pentaxim is a liquid formulation marketed by Sanofi Pasteur.[6]


  1. ^ Use During Pregnancy and Breastfeeding
  2. ^ "Diphtheria and Tetanus Toxoids, Acellular Pertussis, Poliovirus and Haemophilus b Conjugate Vaccine". Drugs.com. Retrieved 15 July 2018.
  3. ^ "Pentacel". U.S. Food and Drug Administration(FDA). STN 125145. Retrieved 15 July 2018.
  4. ^ "Pediacel syringe - Summary of Product Characteristics (SmPC)". Datapharm. 17 April 2019. Archived from the original on 17 October 2019. Retrieved 16 October 2019.
  5. ^ a b "Diphteria Toxoid: Canadian Immunization Guide". Public Health Agency of Canada. December 2014. Archived from the original on 24 September 2019. Retrieved 16 October 2019.
  6. ^ Plotkin SA, Liese J, Madhi SA, Ortiz E (July 2011). "A DTaP-IPV//PRP∼T vaccine (Pentaxim): a review of 16 years' clinical experience". Expert Rev Vaccines. 10 (7): 981–1005. doi:10.1586/erv.11.72. PMID 21749196.