Excitatory amino acid transporter 5

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SLC1A7
Identifiers
AliasesSLC1A7, AAAT, EAAT5, solute carrier family 1 member 7
External IDsOMIM: 604471 MGI: 2444087 HomoloGene: 21327 GeneCards: SLC1A7
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for SLC1A7
Genomic location for SLC1A7
Band1p32.3Start53,087,179 bp[1]
End53,142,632 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001287595
NM_001287596
NM_001287597
NM_006671

NM_146255

RefSeq (protein)

NP_001274524
NP_001274525
NP_001274526
NP_006662

NP_666367

Location (UCSC)Chr 1: 53.09 – 53.14 MbChr 4: 107.97 – 108.01 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Excitatory amino-acid transporter 5 (EAAT5) is a protein that in humans is encoded by the SLC1A7 gene.[5][6]

EAAT5 is expressed predominantly in the retina, has high affinity for the excitatory amino acid L-glutamate. When stimulated by this amino acid, EAAT5 conducts chloride ions.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162383 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000008932 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: solute carrier family 1 (glutamate transporter)".
  6. ^ a b Arriza JL, Eliasof S, Kavanaugh MP, Amara SG (April 1997). "Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance". Proc. Natl. Acad. Sci. U.S.A. 94 (8): 4155–60. doi:10.1073/pnas.94.8.4155. PMC 20584. PMID 9108121.

Further reading[edit]