|Born: May 9, 1879|
|Died: April 21, 1968 (aged 88)|
|September 30, 1904, for the Philadelphia Athletics|
|Last MLB appearance|
|October 10, 1904, for the Philadelphia Athletics|
|Earned run average||6.43|
Frederick Romaine Applegate (May 9, 1879 – April 21, 1968) was a Major League Baseball pitcher in 1904 for the Philadelphia Athletics. Between September 30 and October 10, he started and completed three games, winning 1 and losing 2 with an ERA of 6.43. His lone major league win came against the Washington Senators in his third and final start. The score was 7-6.
A native of Williamsport, Pennsylvania, he died in his hometown at the age of 88.