Interleukin 13 receptor, alpha 1

From Wikipedia, the free encyclopedia
  (Redirected from IL13RA1)
Jump to navigation Jump to search
IL13RA1
Protein IL13RA1 PDB 3BPN.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesIL13RA1, CD213A1, IL-13Ra, NR4, CT19, interleukin 13 receptor subunit alpha 1
External IDsOMIM: 300119 MGI: 105052 HomoloGene: 1198 GeneCards: IL13RA1
Gene location (Human)
X chromosome (human)
Chr.X chromosome (human)[1]
X chromosome (human)
Genomic location for IL13RA1
Genomic location for IL13RA1
BandXq24Start118,727,133 bp[1]
End118,794,535 bp[1]
RNA expression pattern
PBB GE IL13RA1 201888 s at fs.png

PBB GE IL13RA1 210904 s at fs.png

PBB GE IL13RA1 201887 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001560

NM_133990

RefSeq (protein)

NP_001551

NP_598751

Location (UCSC)Chr X: 118.73 – 118.79 MbChr X: 36.11 – 36.17 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1), is a human gene.[5]

The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.[5]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000131724 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017057 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: IL13RA1 interleukin 13 receptor, alpha 1".

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.