Nucleoside-specific porin

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Nucleoside-specific channel-forming protein, Tsx
1tly opm.png
OPM superfamily9
OPM protein1tly

Nucleoside-specific porin (the tsx gene of Escherichia coli) is an outer membrane protein, Tsx, which constitutes the receptor for colicin K and Bacteriophage T6, and functions as a substrate-specific channel for nucleosides and deoxy-nucleosides.[1] The protein contains 294 amino acids, the first 22 of which are characteristic of a bacterial signal sequence peptide. Tsx shows no significant similarities to general bacterial porins.


  1. ^ Bremer E, Martinussen J, Middendorf A, Valentin-Hansen P (1990). "Analysis of the tsx gene, which encodes a nucleoside-specific channel-forming protein (Tsx) in the outer membrane of Escherichia coli". Gene. 96 (1): 59–65. doi:10.1016/0378-1119(90)90341-N. PMID 2265760.
This article incorporates text from the public domain Pfam and InterPro: IPR003055