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Available structures
PDBOrtholog search: PDBe RCSB
AliasesP2RY14, BPR105, GPR105, P2Y14, purinergic receptor P2Y14
External IDsOMIM: 610116 MGI: 2155705 HomoloGene: 15769 GeneCards: P2RY14
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for P2RY14
Genomic location for P2RY14
Band3q25.1Start151,212,117 bp[1]
End151,278,542 bp[1]
RNA expression pattern
PBB GE P2RY14 206637 at fs.png
More reference expression data
RefSeq (mRNA)


RefSeq (protein)


Location (UCSC)Chr 3: 151.21 – 151.28 MbChr 3: 59.11 – 59.15 Mb
PubMed search[3][4]
View/Edit HumanView/Edit Mouse

P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.[5]

The product of this gene, P2Y14 belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.[5]

See also[edit]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000174944 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000036381 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: P2RY14 purinergic receptor P2Y, G-protein coupled, 14".

Further reading[edit]

External links[edit]

  • "P2Y Receptors: P2Y14". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.