Polycentric chromosome

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In genetics, a polycentric chromosome is any chromosome featuring multiple centromeres.[1] Polycentric chromosomes are produced by chromosomal aberrations such as deletion, duplication, or translocation.[citation needed] Polycentric chromosomes usually result in the death of the cell because polycentric chromosomes may fail to move to opposite poles of spindle fiber during anaphase. As a result, the chromosome is fragmented, which causes the death of the cell. In some algae, such as Spirogyra, polycentric chromosomes appear normally.[2]


  1. ^ Neumann P, Navrátilová A, Schroeder-Reiter E, Koblížková A, Steinbauerová V, Chocholová E, et al. (2012-06-21). "Stretching the rules: monocentric chromosomes with multiple centromere domains". PLOS Genetics. 8 (6): e1002777. doi:10.1371/journal.pgen.1002777. PMC 3380829. PMID 22737088.
  2. ^ Godward MB (April 1954). "The 'Diffuse' Centromere or Polycentric Chromosomes in Spirogyra". Annals of Botany. 18 (2): 143–144. doi:10.1093/oxfordjournals.aob.a083387.