In genetics, a polycentric chromosome is any chromosome featuring multiple centromeres. Polycentric chromosomes are produced by chromosomal aberrations such as deletion, duplication, or translocation. Polycentric chromosomes usually result in the death of the cell because polycentric chromosomes may fail to move to opposite poles of spindle fiber during anaphase. As a result, the chromosome is fragmented, which causes the death of the cell. In some algae, such as Spirogyra, polycentric chromosomes appear normally.
- Neumann P, Navrátilová A, Schroeder-Reiter E, Koblížková A, Steinbauerová V, Chocholová E, et al. (2012-06-21). "Stretching the rules: monocentric chromosomes with multiple centromere domains". PLOS Genetics. 8 (6): e1002777. doi:10.1371/journal.pgen.1002777. PMC 3380829. PMID 22737088.
- Godward MB (April 1954). "The 'Diffuse' Centromere or Polycentric Chromosomes in Spirogyra". Annals of Botany. 18 (2): 143–144. doi:10.1093/oxfordjournals.aob.a083387.
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