Provincial Road 280 (PR 280) is a road in the Canadian province of Manitoba. It runs from Provincial Road 391 northwest of Thompson to local streets in Gillam. The route is 291 kilometres (181 mi) long, which during its length, passes several large lakes and intersects with one provincial road, Road 290, just north of Gillam. The route is very scenic, passing through dense forests and rural lands. The route supplies three municipalities, Thompson, Split Lake, and Gillam. Before Road 280 was constructed, the only access to the village of Gillam were via a railroad that ran across the Hudson Bay Railway. This railway serves much of the towns accessible from Road 280 and nearby Road 391. The railway also continues along Road 290 towards Sundance.
Before Route 280 existed, the only ways to the northern terminus town of Gillam was via a nearby airport to the southeast of town and the HBR railroad line that stretched from Thompson to northern parts of Manitoba. Road 280 is the only car access road to Gillam. From its terminus north of Thompson, Manitoba to the town Gillam, PR 280 is classified as a Class A1 Provincial Route. Churchill, on Hudson Bay, can be accessed by VIA RAIL (passenger train "The Hudson Bay", VIA 692 south and VIA 693 north from Winnipeg three days per week) on the Hudson Bay Railway (freight) line. The PR 280 affords access to this more northerly transportation route at a couple of junctions.