60S ribosomal protein L4

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Available structures
PDBOrtholog search: PDBe RCSB
AliasesRPL4, L4, Ribosomal protein L4
External IDsOMIM: 180479 MGI: 1915141 HomoloGene: 748 GeneCards: RPL4
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for RPL4
Genomic location for RPL4
Band15q22.31Start66,498,015 bp[1]
End66,524,532 bp[1]
RNA expression pattern
PBB GE RPL4 201154 x at fs.png

PBB GE RPL4 211710 x at fs.png
More reference expression data
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC)Chr 15: 66.5 – 66.52 MbChr 9: 64.17 – 64.18 Mb
PubMed search[3][4]
View/Edit HumanView/Edit Mouse

60S ribosomal protein L4 is a protein that in humans is encoded by the RPL4 gene.[5][6][7]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L4E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[7]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000174444 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032399 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res. 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.
  6. ^ Bagni C, Mariottini P, Annesi F, Amaldi F (Feb 1994). "Human ribosomal protein L4: cloning and sequencing of the cDNA and primary structure of the protein". Biochim Biophys Acta. 1216 (3): 475–8. doi:10.1016/0167-4781(93)90017-8. PMID 8268230.
  7. ^ a b "Entrez Gene: RPL4 ribosomal protein L4".

Further reading[edit]