Rac is a subfamily of the Rho family of GTPases, small (~21 kDa) signaling G proteins (more specifically a GTPase). When bound to GTP, Rac is activated. In its activated state, Rac participates in the regulation of cell movement, through its involvement in structural changes to the actin Cytoskeleton.
The subgroup include:
- Ridley A. (2006). "Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking". Trends Cell Biol. 16 (10): 522–9. doi:10.1016/j.tcb.2006.08.006. PMID 16949823.
- "Rac", Encyclopedia of Cancer, Springer Berlin Heidelberg, pp. 3133–3133, 2011, ISBN 9783642164828, retrieved 2019-05-13
- Shuai, Yichun; Lu, Binyan; Hu, Ying; Wang, Lianzhang; Sun, Kan; Zhong, Yi (2010-02-19). "Forgetting Is Regulated through Rac Activity in Drosophila". Cell. 140 (4): 579–589. doi:10.1016/j.cell.2009.12.044. PMID 20178749.
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