Electroneutral sodium bicarbonate exchanger 1

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SLC4A8
SLC4A8.png
Identifiers
AliasesSLC4A8, NBC3, NDCBE, solute carrier family 4 member 8
External IDsOMIM: 605024 MGI: 1928745 HomoloGene: 68419 GeneCards: SLC4A8
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for SLC4A8
Genomic location for SLC4A8
Band12q13.13Start51,391,317 bp[1]
End51,515,763 bp[1]
RNA expression pattern
PBB GE SLC4A8 207056 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001033218
NM_021530
NM_001347102

RefSeq (protein)

NP_001035049
NP_001245330
NP_001245331
NP_001245332
NP_001254544

NP_001334031
NP_067505

Location (UCSC)Chr 12: 51.39 – 51.52 MbChr 15: 100.76 – 100.82 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Electroneutral sodium bicarbonate exchanger 1 is a protein that in humans is encoded by the SLC4A8 gene.[5][6]

See also[edit]

Interactions[edit]

SLC4A8 has been shown to interact with Sodium-hydrogen antiporter 3 regulator 1[7][8] and Cystic fibrosis transmembrane conductance regulator.[8]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000050438 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000023032 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Grichtchenko II, Choi I, Zhong X, Bray-Ward P, Russell JM, Boron WF (May 2001). "Cloning, characterization, and chromosomal mapping of a human electroneutral Na+-driven ClHCO3 exchanger". J Biol Chem. 276 (11): 8358–63. doi:10.1074/jbc.C000716200. PMID 11133997.
  6. ^ "Entrez Gene: SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8".
  7. ^ Pushkin A, Abuladze N, Newman D, Muronets V, Sassani P, Tatishchev S, Kurtz I (March 2003). "The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction". Am. J. Physiol., Cell Physiol. 284 (3): C667–73. doi:10.1152/ajpcell.00225.2002. PMID 12444018.
  8. ^ a b Park M, Ko SB, Choi JY, Muallem G, Thomas PJ, Pushkin A, Lee MS, Kim JY, Lee MG, Muallem S, Kurtz I (December 2002). "The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3 salvage transporter human Na+-HCO3 cotransport isoform 3". J. Biol. Chem. 277 (52): 50503–9. doi:10.1074/jbc.M201862200. PMID 12403779.

Further reading[edit]