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edit·history·watch·refresh Stock post message.svg To-do list for Phospholipid:

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I've updated the page a little with some extra general information about phospholipids, although it looks like someone may need to create an article on the Fluid-Mosaic Model used to describe phospholipid movement in cell membranes. I'll leave it to the experts, I think, since I'm not that great at lipid Biochemistry - Agaricus

I've just corrected the contradiction in the paragraph on the ampiphiphatic character of phospholipides. Falk Lieder Aug 25 2005

The main picture on this article is hideous, not to mention misleading. I think it needs a standard picture in addition to what is there already. The current picture shows why it is a polar molecule; this would be useful for describing why it forms membranes, but not for showing what the structure of the molecule is. So that picture might be moved into the body of the article. Fuzzform 02:26, 9 April 2006 (UTC)
I totally agree. Karol 10:12, 9 April 2006 (UTC)

Does anyone else feel that the section title "Synthesis" should be changed to "Biosynthesis", to indicate that the section is about the natural biosynthesis in the cell, as opposed to a synthetic chemical strategy ? I couldn't tell if it was a description of what happens in the cell or what an organic chemist may do to make phospholipids at the bench. "Synthesis" vs. "Biosynthesis" could equally apply as an ambiguity in the articles of many biomolecules, I just noticed it here first. --Pansapiens 06:26, 9 November 2006 (UTC)

This article is badly in need of an expert in the field of biochemistry. Specifically the part that refers to the ethanoamide component.

I personally feel that this page is top notch. Being a professor of biochemistry, I would know this. I am clearly highly superior and you are my subordinates. Well done Wikipedia for making such an outstanding page on the changing trends within Dolce and Gabanna circa 1992... —Preceding unsigned comment added by (talk) 14:11, 11 September 2007 (UTC)

WHY does it say in its simplest form it has a glycerol. That isn't what a phospholipid means, that is what a glycerophospholipid means?? Also the pic misleads others to think it has to have a glycerol.. —Preceding unsigned comment added by Al-jeraiwy (talkcontribs) 23:47, 21 December 2007 (UTC)

(as mentioned earlier) picture is taken from page Glycerophospholipid. and the another picture with two hydrophobic tails doesn't cover all the variety of phospholipids (eg. cardiolipin) VGmonster (talk) 08:18, 13 October 2008 (UTC)

Cardiolipin is a glyercol derivative. Amphipathic character is not defined within the body of the text. —Preceding unsigned comment added by California1985 (talkcontribs) 00:21, 7 September 2009 (UTC)

Unclear. Lipid bilayers occur when hydrophobic tails line up against one another, forming a membrane with hydrophilic heads on both sides facing the water. —Preceding unsigned comment added by California1985 (talkcontribs) 00:29, 7 September 2009 (UTC)

I agree with the suggestion from Pansapiens that the heading "Phospholipid synthesis" should be altered to "Phospholipid biosynthesis." I also concur with Fuzzform and Karol that the graphics need to be improved. I think there should probably be some section on the different categories of phospholipids (phosphatidylcholine, phosphatidylethanolamine, etc.). Overall, I think that this article requires a great deal of expansion, since there is a large amount of information available on this subject in the primary and secondary literature. Anpetu-We (talk) 18:09, 4 October 2009 (UTC)

Concerning an error in the first image [1] of this article: it shows positive charges on the head-groups of the phospholipids and negative charge at the tails. This is wrong. These phosphate groups are negatively charged and charge-balanced by ions in the surrounding solution. The lipid tails are neutral (not charged), but hydrophobic/lyophilic (‘oil-loving’). Samataer (talk) 12:56, 7 May 2012 (UTC)

I cropped the photo to exclude the incorrectly added charges. It may not look as pretty, but it can do until a properly edited photo is found. Superscience71421 (talk) 07:56, 30 November 2016 (UTC)

I was reading about how phospholipids can be used to make aerated chocolate [2]. Should this be mentioned under 'Applications'? This is the first thing I've done on Wikipedia, so I wasn't sure if this was important enough to put into the article. Irfan434 (talk) 06:44, 3 August 2015 (UTC)

The second picture on the article by veggisaur is missing the glycerol and ought really to be removed (their full name being Glycerophospholipids)


  1. ^
  2. ^ Su-Jia, S., Dong, C. and Shi-Chao, X. (2013), The Foaming Abilities of Surfactants in Cocoa Butter. Journal of Food Process Engineering, 36: 544–547. doi: 10.1111/jfpe.12017

Assessment comment[edit]

The comment(s) below were originally left at Talk:Phospholipid/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

I think an entry on phosphatidyl glycerol should be added. I would do it except I don't understand how to add pictures to an article and last time I accidentally uploaded a picture they got mad at me for not sourcing it properly. Lash miller 01:55, 9 November 2006 (UTC)

Last edited at 01:55, 9 November 2006 (UTC). Substituted at 02:53, 30 April 2016 (UTC)

Antiphospholipid antibody syndrome (APLA syndrome or APLS)[edit]

Antiphospholipid antibody syndrome (APLA syndrome or APLS) none as syndrome de Soulier et Boffa or Hughes’ syndrome.

What change with this disease in the Phospholipid synthesis, in signal transduction ?

"Sources" : restrict the consumption of products with a high phospholipid content can have benefits ?

"Sterols contribute to membrane fluidity by hindering the packing together of phospholipids."  So, consuming sterols can decrease blood hypercoagulable and lipids heap ?

For people with APLS, is there a phospholipid to favor ?

I think those answers can be interesting to understand phospholipids chemistry.

Krismie33 (talk) 05:43, 26 December 2019 (UTC)