Talk:Steroid

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search

WikiProject Guild of Copy Editors
WikiProject iconA version of this article was copy edited by Miniapolis, a member of the Guild of Copy Editors, on October 23, 2015. The Guild welcomes all editors with a good grasp of English and Wikipedia's policies and guidelines to help in the drive to improve articles. Visit our project page if you're interested in joining! If you have questions, please direct them to our talk page.
 

Importance of Wikipedia article as most general gateway to all information on steroids[edit]

I would note that the Wikipedia Steroid article consistently appears as the first hit using various web search tools, including Google, and has done so for some time. This observation and a survey of article user feedback—on the negative side, because most responders are looking for quick information on anabolics or therapeutics (e.g., principle inhaled and injected corticosteroids)—and of stray comments in this Talk area, taken together, suggest the need for a lead for this article which is the ultimate in user-friendliness (i.e., rapidly redirecting users to other Wiki steroid articles more on point with their interests). To stimulate discussion, here are quotes from the steroid and sterol introductions from EB (their free online product), which might suggest ways to create such a rapidly redirecting lead. After a few days, anyone desiring to should feel free to collapse or otherwise have this take less space:

Steroid...
[Images of steroid hormones of vertebrates (cortisol, corticosterone, aldosterone, progesterone, beta-estradiol, testosterone)]
"any of a class of natural or synthetic organic compounds characterized by a molecular structure of 17 carbon atoms arranged in four rings. [sic.; and some further compounds with fewer rings deriving directly from these.] Steroids are important in biology, chemistry, and medicine. The steroid group includes all the sex hormones, adrenal cortical hormones, bile acids, and sterols of vertebrates, as well as the molting hormones of insects and many other physiologically active substances of animals and plants. Among the synthetic steroids of therapeutic value are a large number of anti-inflammatory agents, anabolic (growth-stimulating) agents, and oral contraceptives.
Different categories of steroids are frequently distinguished from each other by names that relate to their biological source—e.g., phytosterols (found in plants), adrenal steroids, and bile acids—or to some important physiological function—e.g., progesterones (promoting gestation), androgens (favouring development of masculine characteristics), and cardiotonic steroids (facilitating proper heart function).
Steroids vary from one another in the nature of attached groups, the position of the groups, and the configuration of the steroid nucleus (or gonane). Small modifications in the molecular structures of steroids can produce remarkable differences in their biological activities.
This article covers the history, chemistry, biological significance, and basic pharmacology of steroids. ..."


Sterol...
"The most generally abundant steroids are sterols, which occur in all tissues of animals, green plants, and fungi such as yeasts. Evidence for the presence of steroids in bacteria and in primitive blue-green algae is conflicting [sic.; see http://www.ncbi.nlm.nih.gov/pubmed/12519197 and the 80+ forward citations of this work]. The major sterols of most tissues are accompanied by traces of their precursors—lanosterol in animals and cycloartenol in plants—and of intermediates between these compounds and their major sterol products. In mammalian skin one precursor of cholesterol, 7-dehydrocholesterol, is converted by solar ultraviolet light to cholecalciferol, vitamin D3 [a secosteroid], which controls calcification of bone by regulating intestinal absorption of calcium. The disease rickets, which results from lack of exposure to sunlight or lack of intake of vitamin D, can be treated by administration of the vitamin or of the corresponding [secosteroid] derivative of ergosterol, ergocalciferol (vitamin D2).
[images of ergosterol and derived secosteroid ergocalciferol]
Sterols are present in tissues both in the nonesterified (free) form and as esters of aliphatic fatty acids. In the disease atherosclerosis, fatty materials containing cholesterol form deposits (plaques), especially in the walls of the major blood vessels, and vascular function may be fatally impaired. The disease has many contributory factors but typically is associated with elevated concentrations of ..."
While I clearly differ with some of this content (therapeutics not as front and center in their intro as they could be, secosteroids discussed before cholesterol-atherosclerosis though not clearly established as steroids upfront, etc.), the extremely broad coverage of their approach is clear, which in Wikipedia's case would allow for very rapid redirection of readers to the specialty articles that are many readers' true interests. Le Prof.

Still no secosteroids, and term partial synthesis still misused[edit]

With regard to the first issue, see preceding section.

With regard to the second issue, the use of the Heading "Partial synthesis" to present the material that currently appears is at odds with the generally understood meaning of the chemical term "partial synthesis", see:

I don't expect these things to be corrected (because of a persistent personal editor bias), but I will keep calling attention to the discrepancies between literature and article, as time permits. LeProf

External links modified[edit]

Hello fellow Wikipedians,

I have just modified one external link on Steroid. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:

When you have finished reviewing my changes, you may follow the instructions on the template below to fix any issues with the URLs.

As of February 2018, "External links modified" talk page sections are no longer generated or monitored by InternetArchiveBot. No special action is required regarding these talk page notices, other than regular verification using the archive tool instructions below. Editors have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the RfC before doing mass systematic removals. This message is updated dynamically through the template {{sourcecheck}} (last update: 15 July 2018).

  • If you have discovered URLs which were erroneously considered dead by the bot, you can report them with this tool.
  • If you found an error with any archives or the URLs themselves, you can fix them with this tool.


Cheers.—InternetArchiveBot (Report bug) 18:57, 20 September 2017 (UTC)

External links modified[edit]

Hello fellow Wikipedians,

I have just modified one external link on Steroid. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:

When you have finished reviewing my changes, you may follow the instructions on the template below to fix any issues with the URLs.

As of February 2018, "External links modified" talk page sections are no longer generated or monitored by InternetArchiveBot. No special action is required regarding these talk page notices, other than regular verification using the archive tool instructions below. Editors have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the RfC before doing mass systematic removals. This message is updated dynamically through the template {{sourcecheck}} (last update: 15 July 2018).

  • If you have discovered URLs which were erroneously considered dead by the bot, you can report them with this tool.
  • If you found an error with any archives or the URLs themselves, you can fix them with this tool.


Cheers.—InternetArchiveBot (Report bug) 15:53, 6 December 2017 (UTC)