Xanthosine monophosphate

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Xanthosine monophosphate
Xanthosine monophosphate.svg
IUPAC name
5'-xanthylic acid
Other names
xanthine ribotide,
3D model (JSmol)
MeSH Xanthosine+monophosphate
Molar mass 364.206 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Xanthosine monophosphate is an intermediate in purine metabolism.[1] It is a ribonucleoside monophosphate. It is formed from IMP via the action of IMP dehydrogenase, and it forms GMP via the action of GMP synthase. Also, XMP can be released from XTP by enzyme deoxyribonucleoside triphosphate pyrophosphohydrolase containing (d)XTPase activity.[2]

It is abbreviated XMP.[3]

See also[edit]


  1. ^ McMurry, John (2007). Organic chemistry: a biological approach. Cengage Learning. pp. 1007–. ISBN 9780495015253. Retrieved 26 March 2012.
  2. ^ Davies O, Mendes P, Smallbone K, Malys N (2012). "Characterisation of multiple substrate-specific (d)ITP/(d)XTPase and modelling of deaminated purine nucleotide metabolism" (PDF). BMB Reports. 45 (4): 259–64. doi:10.5483/BMBRep.2012.45.4.259. PMID 22531138.
  3. ^ Gogia, S.; Balaram, H.; Puranik, M. (May 2011). "Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate". Biochemistry. 50 (19): 4184–93. doi:10.1021/bi102039b. PMID 21486037.

Further reading[edit]